FEDERAL105d left

Unlocking Dataset Value for AI-Enabled Scientific Discovery

U.S. National Science Foundation

Posted Jul 21, 2026

Deadline
Nov 4, 2026
105 days remaining
Amount
Varies
Status
Open
Geographic Scope
National

Description

This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis.

The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis.

<span>Proposals should address dataset security and integrity. </span><span>Governance and the process for scientific communities to contribute to the datasets should also be addressed. P</span><span>roposals are encouraged to leverage existing resources. These may include</span><span><a href="https://www.nsf.gov/digital/data"><span>NSF data platforms</span></a>, the <a href="https://www.nsf.gov/funding/opportunities/idss-integrated-data-systems-services"><span>NSF Integrated Data Systems and Services program</span></a>, the <a href="https://www.nsf.gov/focus-areas/ai/nairr"><span>NSF-led National AI Research Resource</span></a>,</span> the <a href="https://www.energy.gov/undersecretaryforscience/genesis-mission/genesis-mission">Genesis Mission platform</a>, or other national infrastructure.

NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunitiesthat will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets.

<span>Expanding Participation in STEM, NSF Priorities, and Gold Standard Science:</span>

NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote<span class="apple-converted-space"></span><a title="https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fabout&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498479654%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hc" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fabout&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498479654%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=%2FCCCSIR%2BbxoiV5%2B1TB7cvpsSDEm3xbBHiUwSHLExJao%3D&amp;reserved=0">NSF's mission</a>. Proposers should review the list of<span class="apple-converted-space"></span><a title="https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fupdates-on-priorities&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498507194%7CUnknown%7CTWFpbGZsb" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fupdates-on-priorities&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498507194%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=Q3GoODxs9MLDgKGJnSQEuvlBfoGApbPEekdS%2FoUtMoc%3D&amp;reserved=0">NSF priorities</a><span class="apple-converted-space"></span>and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of<span class="apple-converted-space"></span><a title="https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fpolicies%2Fgold-standard-science&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498529191%7CUnknown%" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fpolicies%2Fgold-standard-science&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498529191%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=FKjMYWT2h2O3dQGRYwuPLJiVjDlXeHhb4tlBf2W3DkE%3D&amp;reserved=0">Gold</a><span class="apple-converted-space"></span><a title="https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fpolicies%2Fgold-standard-science&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498548690%7CUnknown%" href="https://www.nsf.gov/cgi-bin/good-bye?https://gcc02.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nsf.gov%2Fpolicies%2Fgold-standard-science&amp;data=05%7C02%7Cemisawa%40nsf.gov%7C38dc961290314e9e186d08dee74bb115%7C4939bd9435634244904d6e68ffc9b8cf%7C0%7C0%7C639202509498548690%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=RbRtZB5wPjwz0gNaK8ypiBhqGbpAVBY2Agh5z7BpQTQ%3D&amp;reserved=0">Standard Science</a><span class="apple-converted-space"></span>in proposals, as appropriate for the field of science and research modality.

Funding Details

Key Dates

Posted: Jul 21, 2026Deadline: Nov 4, 2026

Quick Facts

Funder Type
Federal Agency
Grant Level
FEDERAL
Last Verified
Jul 22, 2026

Geographic Scope

national

ReferenceGL-76A169

76a16930-7a53-44b2-8b57-aa40c4408786

Intelligence

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